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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF2
All Species:
19.39
Human Site:
S251
Identified Species:
38.79
UniProt:
Q99496
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99496
NP_009143.1
336
37655
S251
Q
T
R
Y
I
K
T
S
G
N
A
T
V
D
H
Chimpanzee
Pan troglodytes
XP_514057
377
41465
V290
A
A
M
A
I
D
P
V
M
D
G
A
S
E
I
Rhesus Macaque
Macaca mulatta
Q8WMN5
377
39081
G292
G
E
P
G
G
P
G
G
G
A
S
D
T
G
G
Dog
Lupus familis
XP_859868
264
29237
G180
T
R
Y
I
K
T
S
G
N
A
T
V
D
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQJ4
336
37605
S251
Q
T
R
Y
I
K
T
S
G
N
A
T
V
D
H
Rat
Rattus norvegicus
Q4KLY4
308
34224
S224
D
P
V
M
D
G
A
S
E
I
E
L
V
F
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422295
336
37573
S251
Q
T
R
Y
I
K
T
S
G
N
A
T
V
D
H
Frog
Xenopus laevis
Q66J69
344
38348
T257
Q
T
R
Y
V
K
T
T
A
N
A
T
V
D
H
Zebra Danio
Brachydanio rerio
Q803I4
336
37521
S251
Q
T
R
Y
I
K
T
S
G
N
A
T
V
D
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VB08
435
47237
T336
L
V
F
K
P
H
P
T
E
M
S
A
D
N
Q
Honey Bee
Apis mellifera
XP_393984
403
44539
I295
E
P
L
M
L
N
E
I
E
L
V
F
K
P
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788976
652
73333
L558
A
L
A
S
I
D
H
L
A
K
Y
L
S
M
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.9
53.8
77.9
N.A.
99.6
90.4
N.A.
N.A.
97.9
71.2
89.2
N.A.
42.9
51.3
N.A.
20.2
Protein Similarity:
100
81.1
66
78.2
N.A.
100
91
N.A.
N.A.
99.1
80.2
93.4
N.A.
56
65.7
N.A.
33.5
P-Site Identity:
100
6.6
6.6
0
N.A.
100
13.3
N.A.
N.A.
100
80
100
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
20
13.3
6.6
N.A.
100
13.3
N.A.
N.A.
100
93.3
100
N.A.
20
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
9
9
0
0
9
0
17
17
42
17
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
9
17
0
0
0
9
0
9
17
42
0
% D
% Glu:
9
9
0
0
0
0
9
0
25
0
9
0
0
9
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
9
0
9
0
% F
% Gly:
9
0
0
9
9
9
9
17
42
0
9
0
0
9
9
% G
% His:
0
0
0
0
0
9
9
0
0
0
0
0
0
9
50
% H
% Ile:
0
0
0
9
50
0
0
9
0
9
0
0
0
0
9
% I
% Lys:
0
0
0
9
9
42
0
0
0
9
0
0
9
0
0
% K
% Leu:
9
9
9
0
9
0
0
9
0
9
0
17
0
0
9
% L
% Met:
0
0
9
17
0
0
0
0
9
9
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
9
0
0
9
42
0
0
0
9
0
% N
% Pro:
0
17
9
0
9
9
17
0
0
0
0
0
0
9
0
% P
% Gln:
42
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
9
42
0
0
0
0
0
0
0
0
0
0
0
17
% R
% Ser:
0
0
0
9
0
0
9
42
0
0
17
0
17
0
0
% S
% Thr:
9
42
0
0
0
9
42
17
0
0
9
42
9
0
0
% T
% Val:
0
9
9
0
9
0
0
9
0
0
9
9
50
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
42
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _